HDAC4 and epilepsy: Among these, the numbers of variants annotated to curated epilepsy, seizure-associated, and morbid OMIM genes were 6, 22, and 45, respectively (Figure 2B), and HDAC4 c.2851A>T (p.Arg951*) in IS01 is the only non-silent variant in curated epilepsy or seizure-associated genes.