ACE2 and COVID-19: We believe that the results outlined here will be helpful in efforts towards thwarting this new wave of COVID-19 by enabling discovery of potent inhibitors of ACE2-S1-RBD interaction (Andersen et al., 2020; Choudhary et al., 2020; Shang, 2020; Walls, 2020; Wrapp et al., 2020) or the development of high affinity ACE2 variants for use as decoys (Chan et al., 2020; Glasgow et al., 2020; Chan et al., 2021; Jing and Procko, 2021).