YAP1 and malignant colon neoplasm: Next, the colon cancer cell lines overexpressing circPPP1R12A-73aa were treated with a Yes-associated protein 1(Yap1) specific inhibitory peptide 17, which showed that peptide 17 significantly alleviates the promotion of the proliferation, migration, and invasion abilities of colon cancer cells by circPPP1R12A-73aa overexpression (42).