ITGA2 and astrocytoma (excluding glioblastoma): In this study, we have found that a specific polymorphism in the gene coding for a chain of integrin α2β1 (corresponding to the ITGA2 BglII site) was associated with differences in survival of patients with low-grade astrocytoma, with one specific variant (ITGA2 BglII +/+) being overrepresented in grade II astrocytoma cases compared to control individuals.