HLA-DQA1 and leukoencephalopathy with calcifications and cysts: In Future studies, the specific mechanisms by which HLA-DQA1 and IL-34 affect survival will be further explored, and the influence of HLA-DQA1 activation on the antitumor effect of RCC will be further investigated, as well as the possible role of IL-34 as a cytokine therapy in LCC.