Univariate Cox regression showed that AFP of > 1000 ng/mL, tumor numbers, maximal tumor diameter, a sum of tumor diameters, and TNM stage were the risk factors for HCC-related death, and multivariate Cox regression revealed that tumor-related characteristics, such as AFP of > 1000 ng/mL, tumor numbers, and maximal tumor diameter were the independent risk factors for HCC-related death (Table 1). The gene discussed is AFP; the disease is neoplasm.