AFP and hepatocellular carcinoma: In 108 patients who met the Milan criteria and 125 patients who met “Up-to-seven” criteria in our study, AFP of > 1000 ng/mL was a significant risk for HCC recurrence (hazard ratio [HR]: 21.6; 95% confidence interval [CI]: 3.8–123.1; P = 0.001 and HR: 17.3; 95% CI: 3.4–88.6; P = 0.001, respectively).