YTHDF2 is expressed at low levels in HCC, and m6A methylation mediated by YTHDF2 can improve the half-life of lncCY, further promoting the stability of the downstream gene BMI1 mRNA and activating the Wnt-β-catenin signaling axis to affect the proliferation, migration and invasion of HCC (57) (Figure 3B). The gene discussed is BMI1; the disease is hepatocellular carcinoma.