Table 5 shows that after adjusting for age, gender, marital status, education level, ever smoking, ever drinking, self-comment about health, hypertension, dyslipidemia, BMI, depressive symptoms, and cognition function at baseline, the models showed that TG concentrations were negatively associated with cognitive function among prediabetes patients (unstandardized β estimate = −0.004, 95%CI = −0.007 ~ −0.001), and Hs-CRP was significantly associated with cognitive decline among diabetes patients (unstandardized β estimate = −0.065, 95%CI = −0.122 ~ −0.009). The gene discussed is CRP; the disease is metabolic syndrome.