AFP and hepatocellular carcinoma: Returning to our data, DXR-injected rats had higher levels of the tumor indicators CA19.9 and AFP in serum which is in line with the observations by Hozayn et al. [60] but differ from those by Attallah et al. [77] who found that serum AFP and CA 19.9 indicators were nonsignificantly altered by all tested dosages of the hepatotoxin, furfural, in the early identification of hepatocellular carcinoma (HCC).