Returning to our data, DXR-injected rats had higher levels of the tumor indicators CA19.9 and AFP in serum which is in line with the observations by Hozayn et al. [60] but differ from those by Attallah et al. [77] who found that serum AFP and CA 19.9 indicators were nonsignificantly altered by all tested dosages of the hepatotoxin, furfural, in the early identification of hepatocellular carcinoma (HCC). The gene discussed is AFP; the disease is neoplasm.