CRP = C-reactive protein; AKI = acute kidney injury; LDH = lactate dehydrogenase; DD = D-dimer; DD 3x = three-fold increase in D-dimer; DD 6x = six-fold increase in D-dimer; PT = prothrombin time; DVT = deep vein thrombosis; SVP = superficial vein phlebitis; IMPROVE = International Medical Prevention Registry on Venous Thromboembolism; IVM = invasive mechanical ventilation. The gene discussed is F2; the disease is deep vein thrombosis.