Marijt and colleagues identified a human HLA-A2-binding TEIPP derived from the LDL Receptor Related Protein Associated Protein 1 (LRPAP1) signal sequence (LRPAP121-30) common to different type of tumors, including melanoma, lymphoma, colon and renal cell carcinoma (53). The gene discussed is LRPAP1; the disease is renal cell carcinoma.