Surprisingly, m1A also has such potential, as regulators of m1A modification markedly affected glioma prognosis, with NML, TRMT6, TRMT10C, TRMT61B, ALKBH1, ALKBH3, YTHDF1, YTHDF2, and YTHDF3 as risk factors but YTHDC1 as a protective factor (Figure 2). The gene discussed is YTHDF1; the disease is central nervous system cancer.