High serum levels of CCL3, CCL4 (158), CCL28 (159), CXCL5 (160), CXCL8 (42, 161), and CXCL13 (92) as well as expression of CXCL16 mRNA (162) indicate an adverse prognosis in CRC patients. The gene discussed is CXCL13; the disease is colorectal carcinoma.