CCL2 and neoplasm: Bioinformatics analyses about the relationship between the 12-chemokine (CCL2 (chemokine C–C motif ligand 2), -3, -4, -5, -8, -18, -19, -21, CXCL9 (chemokine C–X–C motif ligand 9), -10, -11, -13) signature and immune inflammation have identified that high signature significantly linked to more tumor-infiltrating immune cells, such as cytotoxic T lymphocytes, B cells, monocytes, and myeloid dendritic cells (DCs) (14).