Further analysis of the relationships between the level of sPD-L1 or IL-10 and the histopathological characteristics of IBCa demonstrated that there were no significant associations with histological grade, lymph node metastasis, TNM stage, tumor size, ER status, or PR status (P > 0.05 for all; Table 5). This evidence concerns the gene ESR1 and metastatic malignant neoplasm in the lymph nodes.