However, it has been recently demonstrated that mice vaccinated with the second-generation recombinant BCG30 vaccine and treated with the molecule inhibitor of the IL-10/STAT3 axis, 5,15-diphenyl porphyrin (DPP), after challenge with Mtb aerosol infection resulted in the increased proliferation of central and effector memory T cells compared with untreated mice (32). The gene discussed is STAT3; the disease is infection.