Cluster #0, namely, cardiovascular disease, was the largest cluster consisting of 123 references, followed by disease activity (cluster #1), differential expression (cluster #2), new insight (cluster #3), complex (cluster #4) and related cytokine (cluster #5), mast cell (cluster #6), disease pathogenesis (cluster #7), epidermal barrier (cluster #8), and IL-1f5 (cluster #9). The gene discussed is IL36RN; the disease is cardiovascular disorder.