The results of GFAP immunostaining showed that compared with WT mice, the activation of astrocytes in the brain of model group mice was significantly increased (Figures 9A,B, p < 0.0001), while TS could significantly reduce the positive staining area of GFAP (Figures 9A,B), suggesting that TS could inhibit the excessive activation of astrocytes in the brain of AD mice. The gene discussed is GFAP; the disease is Alzheimer disease.