High-dose TS treatment could significantly increase the content of antioxidant SOD, GSH and the ratio of GSH/GSSG (Figures 8E,F,H, p < 0.05, p < 0.01, p < 0.01, respectively), and decrease the content of GSSG (Figure 8G, p < 0.05) in the brain of AD mice. Here, SOD1 is linked to Alzheimer disease.