Furthermore, Vnn1 is expressed by the centrilobular hepatocytes and is involved in lipid and xenobiotic metabolism (Bartucci et al., 2019), whereas Pex11a (peroxisomal biogenesis factor 11 alpha) is involved in peroxisome maintenance and proliferation associated with dyslipidemia (Chen et al., 2018). This evidence concerns the gene PEX11A and metabolic syndrome.