In the present study, we found that the phosphorylation level of FGFR1 and that of its intracellular substrate FRS2, as well as the protein levels of glucose transporter type 1 (GLUT-1), were significantly increased in the livers of mice with streptozotocin (STZ)-induced diabetes after gavage administration of JQJTT. This evidence concerns the gene SLC2A1 and diabetes mellitus.