Once activated, FGFR1 exerts positive effects on hypoglycemia and lipid reduction by activating the AKT, AMPK, and NF-κB signaling pathways (Yu et al., 2016; Salminen et al., 2017; Guo et al., 2018; Wang et al., 2018). This evidence concerns the gene AKT1 and Hypoglycemia.