Existing evidence suggests the crucial role of JMJD6 as a tumorigenic factor in several cancers, and the high expression of JMJD6 was found to promote the proliferation and survival of tumor cells and predicted the dismal prognosis of patients (Wang et al., 2014; Wong et al., 2019; Biswas et al., 2020). The gene discussed is JMJD6; the disease is cancer.