Furthermore, the qPCR results indicated the mRNA expression levels of JMJD6, ANKZF1, CITED2, and ENO3 was obviously decreased in pancreatic cancer cells versus the normal pancreatic ductal epithelial cells, whereas those of LDHA, TES, and SIAH2 were oppisite (Figure 6). Here, SIAH2 is linked to pancreatic neoplasm.