In the functional analysis of the module, it can be found that mainly involves Coronavirus disease-COVID-19 and Rheumatoid arthritis disease modules and Toll-like Receptor Cascades, Toll-like receptor signaling pathway, NF-kappa B signaling pathway, MAPK signaling pathway, TNF signaling pathway, IL-17 signaling pathway, Th17 cell differentiation signaling pathway modules (Figure 3). The gene discussed is TNF; the disease is COVID-19.