Among the laboratory parameters, the need for ventilation was associated with leukocytosis (p = 0.012), neutrophilia (p = 0.031) and lymphopenia (p = 0.011), as well as CRP (p < 0.001), PCT (p < 0.001), LDH (p < 0.001), IL-6 (p = 0.024), BUN (p = 0.001), creatinine (p = 0.001), PaO2 (p = 0.001), and SaO2 (p < 0.001) (Table 2). The gene discussed is CRP; the disease is Increased total leukocyte count.