In the multivariate Cox regression model, LVMI and NT-proBNP were positively associated with the risk of HF readmission, respectively (NT-proBNP: HR = 1.05, 95%CI 1.01–1.10; LVMI: HR = 1.14, 95% CI: 1.02–1.27). This evidence concerns the gene NPPB and hydrops fetalis.