INS and infection: When performing KEGG analysis, we acquired 23 terms, including metabolic, myocardic, and insulin signaling pathways, besides several infection-/inflammation-related annotations, such as “pathogenic Escherichia coli infection,” “leukocyte transendothelial migration,” “antigen processing and presentation,” “bacterial invasion of epithelial cells,” “herpes simplex infection,” “biosynthesis of antibiotics,” “hepatitis C,” “shigellosis,” “viral myocarditis,” “influenza A,” and “T-cell receptor signaling pathway” (Figure 5D).