Further explanatory approaches throughout the literature included immune-mediated lysis of CD20 antigen-presenting platelets or complement-activation through circulating soluble CD20 antigen.9 Recently, Hinterleitner et al10 demonstrated the transfer of programmed death-ligand 1 (PD-L1) from PD-L1 expressing non-small cell lung cancer cells to platelets in vitro and in vivo. Here, CD274 is linked to non-small cell lung carcinoma.