Yoshida et al. conducted experiments by comparing GD2/GM2 overexpressing melanoma cells with B4GALNT1 expression and GD2/GM2 negative melanoma cells without B4GALNT1 expression, and their results showed that the GD2/GM2 overexpressing cells with B4GANT1 expression had significantly higher ability of anchorage-independent growth—a critical factor for tumorigenesis and exacerbation of malignancy—than the GD2/GM2 negative group [3]. Here, B4GALNT1 is linked to melanoma.