Li and coworkers demonstrated that patients with elevated SRPX2 expression are related to shorter disease-free survival (DFS) and overall survival (OS) than patients with low SRPX2 expression by detecting 200 tissue microarray specimens from patients (79 training and 121 validation) with curative pancreatectomy for pancreatic ductal adenocarcinoma [17]. The gene discussed is SRPX2; the disease is pancreatic ductal adenocarcinoma.