It was identified that the cytokine-cytokine receptor interaction (28 DEP), IL-17 signaling pathway (12 DEP), JAK-STAT signaling pathway (12 DEP), chemokine signaling pathway (10 DEP), TNF signaling pathway (8 DEP), Th17 cell differentiation (7 DEP), PI3K-Akt signaling pathway (7 DEP), C-type lectin receptor signaling pathway (6 DEP), Th1 and Th2 cell differentiation (5 DEP), and Toll-like receptor signaling pathway (5 DEP) were significantly enriched between tumor tissues and serum in the KEGG pathway analysis (Figure 4(i)). Here, TNF is linked to neoplasm.