AKT1 and viral infectious disease: Host cell phosphatidylinositol 3-kinase (PI3K)/Akt signaling seems to be a sentinel pathway after virus infection and take part in a number of physiological changes in the process of virus infection, including IBDV growth (Wei et al., 2011), virus entry into cells (Ye et al., 2017), and inhibition of host cell autophagy (Zhang et al., 2020).