Liu et al. also demonstrated the therapeutic potential of hUC-MSCs on CIA in DBA/1 mice and showed that upon injecting the cells through IP, a reduction in the severity of arthritis was observed with reduced levels of proinflammatory cytokines and chemokines (TNF-α, IL-6, and monocyte chemoattractant protein-1 (MCP1)), induction of Tregs, and increased levels of IL-10 [49]. The gene discussed is CCL2; the disease is arthritic joint disease.