ERBB2 and breast cancer: To examine the role of BLNK in the regulation of anoikis of ErbB2-overproducing breast cancer cells by a complementary approach, we generated a variant of MCF-ErbB2 cells MCF-ErbB2-BLNK in which exogenous BLNK expression is controlled by the doxycycline-inducible promoter (Fig. 4C).