Previous research reported that PSMB8, PSMB9 and PSMB10 expressed at significantly abundant levels in dendritic cells, monocytes, and CD8+ T-cells in idiopathic inflammatory myopathies, which correlated highest with STAT1, IRF1 and IFN-γ expression [24]. The gene discussed is IRF1; the disease is idiopathic inflammatory myopathy.