Although the analysis of explanted resident hearts provided no new information on the progression of DCM, higher expressions of ACE2 and GlycACE2 were observed in explanted hearts from T2DM patients regardless of the cause of HF (Figs. 4 and 5) to get insight into the pathophysiology of end-stage HFrEF along with diabetes, as previously described [14]. The gene discussed is ACE2; the disease is familial dilated cardiomyopathy.