LRRK2 and Parkinson disease: We further examined the levels of phospho-αS and phospho-Rab10 in different brain regions of the patient with LRRK2 G2385R, including the frontal, temporal, occipital, entorhinal cortexes, and cerebellum, comparing with those in the frontal cortex of non-PD control-1 and PD-1 groups (Fig. 2e–g).