To further unravel the biological significance of USP7-TAZ axis in HNSCC, we extracted the gene candidates positively associated with USP7 or TAZ in TCGA-HNSC samples (Spearman’s correlation >0.3) and found 440 overlapped genes which were further subjected to GO and KEGG analyses. Here, USP7 is linked to head and neck squamous cell carcinoma.