Complementarily, correlation analyses of USP7 expression and Hippo-YAP/TAZ cancer signatures revealed that its mRNA abundance was significantly correlated with three previously reported Hippo-YAP/TAZ signatures using TCGA-HNSC dataset (p < 0.05, Supplementary Fig. 13A) [9, 34, 45]. This evidence concerns the gene WWTR1 and cancer.