EIF5A2 and non-small cell lung carcinoma: CCK8 assays showed that compared with the negative control, cisplatin-induced death of A549 and NCI-H1299 cells decreased significantly after eIF5A2 knockdown, and increased after eIF5A2 overexpression (Fig. 4D), indicating that eIF5A2 is involved in cell processes related to cisplatin resistance in NSCLC.