VIL1 and intestinal cancer: Intestinal cancers from the autochthonous Vil1-CreERT2;KrasG12D;p53fl/fl;Rosa26N1ICD/+ (KPN) line were digested and cell suspensions were subjected to established protocols for cell segregation and organoid generation, previously used to enrich for CBCs (Merlos-Suarez et al., 2011) and RSCs (Yui et al., 2018) from mouse models.