CD8A and neoplasm: Consistent with this, KPA tumours were of lower grade compared toKP tumours, had a lower percentage of mitotic cells and showed a moderateCD8+ T cell infiltration –although most CD8+ T cellsaccumulated at the periphery of the tumours (Fig.2D-G and supplementary Fig. 3C).However, KPA tumours grew at similar rates to KP tumours (Supplementary Fig. 3D),suggesting other mechanisms triggered by APOBEC3B expression could affect tumourgrowth.