Furthermore, we observed significantly more IFNγ spots byELISpot analysis from CD8+ T cells isolated from KPAR tumours treatedwith anti-CTLA-4 compared to isotype control when pulsing with the eMLV envelopepeptide, indicating that eMLV-specific T cells expand in response toimmunotherapy (SupplementaryFig. 8B). The gene discussed is CTLA4; the disease is neoplasm.