RAG1 and neoplasm: AZ-8037 treatment caused marked tumour regression in bothimmune-competent and Rag1-/- mice, however theresponse was more durable in immune-competent mice as all tumours remainedresponsive during the duration of treatment whilst tumours inRag1-/- mice began to grow back beforetermination of treatment (Fig. 6A, Supplementary Fig.10A).