Interestingly,ELISpot analysis revealed that the major MHC-I restricted epitope arising fromthe envelope glycoprotein (env) of Emv2, theendogenous ecotropic murine leukaemia retrovirus (eMLV) in C57BL/6J mice,induced IFNγ secretion from splenocytes harvested from KPAR1.3 tumour-bearingmice (Fig. 3E). Here, ERVW-1 is linked to neoplasm.