Thus, HBV DNA >2000 IU/mL (p = .004), BMI (p = .023), AFP more than 200 ng/mL (p < .001), tumour counts (p = .050), maximal tumour diameter (p< .001), macrovascular invasion (p < .001), microvascular invasion (p = .014), TNM stage (p = .004), and MELD score (p = .086) were included in the multivariate analysis. This evidence concerns the gene AFP and neoplasm.