The more precise localization of tumor lesions in patients with BCR by 89Zr-labeled PSMA PET/CT is likely to have consequences for therapy management, e.g., in our cohort of patients, radiotherapy treatment was adjusted for all 5 patients who received subsequent salvage radiotherapy (either minor adjustments as, e.g., additional boost or major adjustments as e.g. extension of radiation field). Here, BCR is linked to neoplasm.