Multivariate analysis showed that CD4+ cell count 350-500 cells/μL (OR = 1.72, 95% CI: 1.26-2.38), CD4+ cell count >500 cells/μL (OR = 2.49, 95% CI: 1.85-3.38), and FPG >6.2 mmol/L (OR = 2.08, 95% CI:1.64-2.65) were risk factors for hyperlipidemia. The gene discussed is CD4; the disease is hyperlipidemia.