Also, Septin7 deficiency alters the morphology of mature neurons (Tada et al., 2007; Xie et al., 2007; Cho et al., 2011; Yadav et al., 2017), leading to neurological disorders such as Alzheimer’s disease, schizophrenia, and neuropsychiatric lupus erythematosus. Here, SEPTIN7 is linked to early-onset autosomal dominant Alzheimer disease.