It should be noted, however, that such effects of tamoxifen were administered to mice with impaired muscle function, that is, to mdx mice (mouse model of Duchenne muscular dystrophy) (Dorchies et al., 2013), to FKRPP448L mutant mice with dystroglycanopathy (Wu et al., 2018), and to Mtm1 knockout mice (murine model of myotubular myopathy) (Maani et al., 2018). Here, MTM1 is linked to neuromuscular disease caused by qualitative or quantitative defects of alpha-dystroglycan.