For instance, lower expression of the liver-specific miRNA miR-122 is associated with the hyperactivity of oncogenic pathways and the development of hepatocarcinogenesis[37], and the miR-885-5p was reported to inhibit aerobic glycolysis by targeting the hexokinase 2 (HK2) and impede the malignant features of liver cancer[38]. The gene discussed is HK2; the disease is liver cancer.