NEK2 and cervical squamous intraepithelial neoplasia: We found that the upregulation of CCND1, FOXA1, NEK2, MAD2L1, PIK3CA, KIF18A and KIF11 induced CIN, with upregulation of CCND1, FOXA1 and NEK2 having the biggest effect and KIF11 upregulation showing a pronounced increase in the number of micronuclei.