Analysis of the TISIDB database showed that PBRM1 abnormalities (including gene expression, mutation, CNA and gene methylation) were significantly associated with a variety of TILs, including activated CD4 (Figure 5A) and CD8 T cells (Figure 5B), activated dendritic cells, monocytes, dendritic cells and natural killer cells (NK cells) (Table 2), indicating that they can significantly contribute to tumor immune activity. Here, PBRM1 is linked to neoplasm.