The results of cellular experiments showed that in the lactic acid environment, the MCL-microsphere group had high survival of NPC with higher levels of ACAN and COL2 expression and downregulated expression of genes for inflammatory factors (IL-1β and TNF-α) and catabolic factors (e.g., MMP-3, MMP-13). The gene discussed is MMP13; the disease is nasopharyngeal carcinoma.