The International Prognostic Score (IPS) is composed of seven potential risk factors [albumin < 4 g/dl, hemoglobin < 10.5 g/dl, male, age ≥ 45 years, stage IV disease, leukocytosis, and lymphocytopenia (5)] and is intensively applied for risk classification. Here, ALB is linked to Increased total leukocyte count.