identified an association between COX1 rs10306110 polymorphism and low intake of docosahexaenoic acid (DHA), a fatty acid with anti-inflammatory properties, with an increased risk of colon cancer (OR = 1.6, 95% CI: 1.1–2.3, adjusted P = 0.06) (38). Here, PTGS1 is linked to malignant colon neoplasm.