ALOX15 and rectal cancer: The results showed that the rs2073438 polymorphism of ALOX 12 was related to a lower risk of rectal cancer (OR = 0.66, 95% CI: 0.42–1.04), while the rs4796535 and rs2619112 polymorphisms of ALOX15 were associated with an increased risk of rectal cancer (OR = 1.43, 95% CI: 1.03–1.97 and OR = 1.13, 95% CI: 0.85–1.55, respectively) (22).