As such, CACNA1I variants proposed to contribute to sleep rhythms (Astori et al., 2011; Ghoshal et al., 2020) are also implicated in the development of complex neuropsychiatric disorders including autism and schizophrenia (Lu et al., 2012; Andrade et al., 2016; Lory et al., 2020; El Ghaleb et al., 2021). This evidence concerns the gene CACNA1I and autism.