However, 15 kinds of plasma cytokines (eotaxin-2, IL-1β, IL-1ra, IL-6, IL-6R, IL-11, IL-12p40, IL-16, MCSF, MIG, MIP-1α, MIP-1d, PDGF-BB, TIMP-1, and TIMP-2) hardly changed in NSCLC patients, in comparison with HC. This evidence concerns the gene TIMP1 and non-small cell lung carcinoma.