In addition, we detected that the interleukin-1 receptor antagonist (IL-1ra) had a positive relationship with MDSCs and CD68+CD163+M2-like macrophages but the tissue inhibitor of metalloproteinases-2 (TIMP-2) and tumor necrosis factor receptor-I (TNF RI) were only correlated with MDSCs in NSCLC patients during radiotherapy. This evidence concerns the gene TIMP2 and non-small cell lung carcinoma.