17 kinds of plasma cytokines (G-CSF, GM-CSF, ICAM-1, IFN-γ, IL-1α, IL-2, IL-4, IL-5, IL-7, IL-8, IL-10, IL-12p70, IL-13, IL-15, IL-17, TNF-α, and TNF-β) were obviously decreased in NSCLC patients, in comparison with HC. This evidence concerns the gene IL4 and non-small cell lung carcinoma.